Region-Specific Neurotrophin Imbalances in Alzheimer Disease
نویسندگان
چکیده
منابع مشابه
Region-specific neurotrophin imbalances in Alzheimer disease: decreased levels of brain-derived neurotrophic factor and increased levels of nerve growth factor in hippocampus and cortical areas.
BACKGROUND Nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), neurotrophin 3 (NT-3), and neurotrophin 4/5 (NT-4/5) are members of the neurotrophin gene family that support the survival of specific neuronal populations, including those that are affected by neurodegeneration in Alzheimer disease (AD). OBJECTIVE To determine whether neurotrophin protein levels are altered in th...
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ژورنال
عنوان ژورنال: Archives of Neurology
سال: 2000
ISSN: 0003-9942
DOI: 10.1001/archneur.57.6.846